AMPERE COMPUTING LLC

AMPERE Computing Launches Crest Enamel Care – Revolutionizing Oral Health Data Analysis

SANTA CLARA, CA – October 26, 2023 – AMPERE Computing LLC, a leading innovator in high-performance computing solutions, today announced a collaboration with Procter & Gamble to significantly enhance the data analysis powering the development and personalization of Crest Enamel Care toothpaste. This partnership leverages AMPERE’s cutting-edge hardware and software to unlock deeper insights into enamel health and individual oral microbiome profiles, paving the way for more effective and targeted oral care solutions. For years, Crest has been a household name in oral hygiene, trusted by families worldwide. Now, with Crest Enamel Care, they’re going beyond simply cleaning teeth – they’re focusing on strengthening enamel from the inside out. But developing a toothpaste that genuinely tackles enamel erosion and rebuilds strength requires a ton of data. That’s where AMPERE Computing comes in. “Think about it,” explains Dr. Emily Carter, Lead Scientist at P&G’s Oral Care division. “Enamel is amazing stuff – super strong, but also surprisingly delicate. Everyone’s mouth is different – diet, habits, even genetics play a role in how quickly enamel breaks down. We were collecting huge amounts of data – clinical trials, microbiome studies, consumer feedback – but analyzing it all quickly and effectively was a real bottleneck.” AMPERE Computing, based right here in Santa Clara, specializes in building powerful computing systems designed to handle massive datasets. They don’t make toothpaste; they make the brains that help toothpaste companies create better products. Founded on the principle that data is the key to innovation, AMPERE has been quietly powering breakthroughs in fields like drug discovery, financial modeling, and – now – oral health. “Traditional computing just wasn’t cutting it,” says Mark Johnson, CEO of AMPERE Computing LLC. “The scale and complexity of P&G’s data required a fundamentally different approach. We’re talking about millions of data points per individual – things like bacterial composition, enamel hardness measurements, dietary habits, and pH levels. Analyzing all that to find meaningful patterns? That's a job for our specialized systems." So, what exactly is Crest Enamel Care and how is AMPERE helping? Crest Enamel Care isn’t your average fluoride toothpaste. It’s formulated with a unique mineral complex designed to actively bind to and rebuild enamel. It doesn't just protect against acid attacks; it reverses early stages of enamel damage. “We knew the science was solid,” adds Dr. Carter. “But truly understanding how effectively the minerals were working, and identifying which individuals would benefit the most? That required analyzing the data from our clinical trials in a way we simply couldn’t do before.” AMPERE’s system, dubbed “Athena,” uses a highly parallel processing architecture. Think of it like having thousands of mini-computers working together on a single problem. This allows Athena to sift through massive datasets much faster than traditional computers, identifying subtle patterns and correlations that would otherwise be missed. “We were able to analyze microbiome data to identify specific bacterial strains associated with enamel erosion,” explains Sarah Chen, AMPERE’s Data Science Lead. “This allows P&G to tailor the formulation of Crest Enamel Care to target those specific strains, creating a more effective product for a wider range of individuals.” Here's a breakdown of how AMPERE’s technology is directly impacting Crest Enamel Care: Personalized Formulation: By analyzing individual microbiome profiles, AMPERE helps P&G understand which bacterial imbalances are most common and how they contribute to enamel erosion. This allows for future customization of Crest Enamel Care to address specific needs. Faster Clinical Trial Analysis: Traditionally, analyzing data from clinical trials could take months. AMPERE’s technology cuts that down to weeks, accelerating the development of new and improved oral care products. Improved Efficacy Testing: AMPERE’s system allows for more precise measurement of enamel remineralization, ensuring that Crest Enamel Care is truly delivering on its promise of strengthening enamel. Identifying At-Risk Individuals: By analyzing demographic and lifestyle data, AMPERE can help identify individuals who are most at risk of enamel erosion, allowing for targeted preventative measures. Optimizing Ingredient Combinations: The system allows P&G scientists to rapidly test different ingredient combinations to find the most effective formula for enamel repair and protection. “This isn't just about creating a better toothpaste,” says Mark Johnson. “It’s about using the power of computing to improve people’s lives. Stronger enamel means fewer cavities, less sensitivity, and a healthier smile. We’re proud to be partnering with P&G to make that happen.” Crest Enamel Care is now available at major retailers nationwide. While you’re brushing, remember that behind that clean feeling, there’s a powerful engine of data analysis working to keep your smile healthy for years to come. About AMPERE Computing LLC: AMPERE Computing LLC, located at 4655 Great America Parkway, Suite 601, Santa Clara, CA 95054-1236, United States (815-858-7063), is a leading provider of high-performance computing solutions. The company specializes in building customized hardware and software platforms designed to accelerate data analysis and unlock insights in a variety of industries. AMPERE’s mission is to empower innovation through the power of computing. About Procter & Gamble: Procter & Gamble (P&G) is a leading global consumer goods company, with a portfolio of trusted brands that touch the lives of billions of people around the world. P&G’s commitment to innovation and sustainability drives its mission to improve the lives of consumers and communities around the world.

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